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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

马丁沃尔夫(Martin Wolf)
阿斯利·埃尔多安(Asli Erdogan)

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

考虑到波士顿咨询集团(Boston Consulting Group)管理合伙人理查德莱塞(Richard Lesser)的第二任期将于10月结束,该公司可能也将引来变化。然而,由于该公司拒绝就其选举流程及领导人最多可以有几个任期置评,莱塞的未来尚不明确。
[p?izd]

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

据《每日经济新闻》网报道,经过一项最新调查显示,经济和金融类院校毕业生最有'钱'途。国内5大财经类高校毕业生的平均月薪在1万元以上。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

巴黎法新社-1400法国人已经加入圣战组织或者打算这么做,总理ManuelValls周一说。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 建材行业:水泥行业逐步进入淡季
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Until a couple of games ago, Stephen Curry really hadn't thought much about making more NBA history.
Throughout Downsizing, I kept asking myself what the point of all of this was, never engaged by its hodgepodge of themes. I wish the filmmakers had asked that question too.
源于:strike(v 打击;军事进攻;铸造;敲钟;罢工)
We learned that there is new hope for Africans with treatable cancers.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

2014年全年工业利润增长3.3%,为2008年以来最慢。
[spred]
而今年的诺贝尔奖,更是一反过往青睐大型科技成果的传统,将大奖颁给了体积最小的科学新发现。
Big and brassy! Paul McCartney (yes, yes, and also Wings) ushered in a new era of James Bond movies with the theme to Live and Let Die, sending the series careening into a 1970s musical sound as the franchise rebranded itself with a new leading man, Roger Moore. This is an almost maniacally excited song. The melody shifts and spirals and builds and sinks and hardly gives the listener a chance to get their bearings. It's a thrill.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Dealers: Car dealers work toward reducing the paperwork involved in buying a car and the hours it takes to fill it out. That will give them more time to devote to upselling add-ons such as extended warranties, paint and fabric protection, and rust-proofing.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

[s?:'vei]

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

“我们非常确信成交价会达到预测的最高价。”
随着中国收紧法规,中国的黄金公司日益期盼进行海外收购。去年,山东黄金矿业股份有限公司(Shandong Gold Mining)同意以9.6亿美元购买巴里克黄金公司(Barrick Gold)持有的阿根廷贝拉德罗(Valedero)金矿50%的股权。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 荣麟家居启动线上打假
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Reese Witherspoon dreamt of being a non-traditionalist, reportedly wanting to transform the best actress statue she won for Walk the Line into a door knocker or a necklace (“statement” jewellery would not have cut the mustard). Neither option being practical, however, he now stands in her living room.
报告指出,缺少资金和经验是大学生创业者们面临的最大障碍,40%的年轻创业者们依赖于诸如来自银行、投资机构、学校和政府等机构贷款的外部资金。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Consider this: Will the experience enhance your knowledge and play to your strengths? Will it introduce you to new concepts and new people? (All great reasons to say yes!) Will it require you to develop new techniques for managing your team or working with more experienced people? Embrace this challenge and get out of your comfort zone.
如果没有别的,很明显,夏天交易期并不代表NBA赛季的停止,它只是换了个档而已。

Graphical abstract: Diagnostic technologies for COVID-19: a review
From the themed collection: 石家庄一季度拆除17家水泥企业
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

On Tuesday, 17-year-old Thomas Sohmers unveiled a new super fast computer server that uses a fraction of the electricity that a normal computer does.He's showing it off at the Open Compute Project (OCP) Summit happening this week in San Francisco.This computer is the first product from Sohmers' startup, REX Computing, created with 52-year-old co-founder and CTO Kurt Keville.
Two arrests have been made in connection to the shooting death of 14-year-old Lecent Ross, police said Thursday.
The movies were selected from more than 2,000 titles from 100 countries and will be screened in 30 cinemas and colleges around Beijing from April 8 to April 23, Zhang Xiaoguang, deputy head of China Film Archive, said last Thursday.
Charli XCX, 'Number 1 Angel'

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

What’s more, in recognition of their working on the bizarre properties of matter in extreme states and taking their research all the way down to an atomic scale, the Nobel Prize for physics was awarded to three British-born scientists who currently work in the US.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

今年,全球2000强企业来自62个国家,比起2003的首届排行榜的46个国家数量上升了。这些企业总共创造了38万亿美元的营收及3万亿美元的利润,总资产达161万亿美元,总市值则达到44万亿美元。
据新华社今年二月报道,互联网借贷公司"易租宝"之前通过一个巨大的庞氏骗局,从大约90万投资人那里骗取了超过500亿人民币的资金。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

挪威曾为一只企鹅授予爵位。它现在居住在苏格兰的爱丁堡动物园,是那里的企鹅王,它叫尼尔斯·奥拉夫( Nils Olav)。它不仅是一只吉祥物,更是挪威皇家护卫队的名誉上校。2008年8月15日,国王哈拉尔五世(King Harald V)授予奥拉夫爵位,并在授予典礼上声明“奥拉夫在各方面都有资格获得骑士爵位的荣誉和尊严”。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

It’s been one of the worst years for investment decision-making on record, almost across the board. No strategy worked consistently, save for the type of shareholder activism that only a handful of Wall Street’s billionaire titans are able to engage in.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

汉口滨江的居民数周前就已将财产转移。
刘易斯说道:“人们不能像这样,抛弃他们的宠物。每个人都有悉心照料自己宠物的法律义务。”
No, this doesn't mean you should abandon your LinkedIn profile for fear of a suspicious boss. But it does mean you should be more careful. For one, turn off your activity broadcasts so that every savvy move you make isn't announced to your entire network. Here's how: From the homepage, hover over your photo in the top right corner, and click on "Privacy & Settings." From this page, click "Turn on/off your activity broadcasts."
com共同,miss=mit送-共同送东西到指定处-委托com共同,mission(n 使命,任务)-受了别人的委托,说明你得到了别人的信任,所以这是一种使命。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

crime罪行+al表名词,“人,物,状态”→犯罪分子
这一数字是曼谷市人口(1000万)的两倍多。
2013 Rank: 12
adj. 可能的,潜在的
我们可以看到时空涟漪的源头。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

15. “The End of the Tour” (James Ponsoldt)
In addition, the top-ranking cities typically performed poorly in costs and culture and lifestyle. China's "cities of opportunity" continue to face challenges when it comes to building cities that satisfy the needs of the populace and provide a high quality of life.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

In 55th place, University of Edinburgh Business School regains the rank it held two years ago. The school dropped down the tables last year after failing to make it into the Masters in Management ranking. The University of Bradford School of Management recorded its best progression, aided by the school’s first appearance in the ranking of the top 100 Executive MBAs.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

6.不是故事的结局不够好,而是我们对故事要求太多。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

The ministry said that it had no tolerance for cheating and had asked public security departments to conduct an investigation.
China’s outbound non-financial investment fell 40.9 per cent during the ten months through October, according to official figures, reflecting the enduring impact of strict capital controls.
13. Even Better In October, The Los Angeles Times reported that the Equal Employment Opportunity Commission was investigating gender discrimination in the industry, just as the American Civil Liberties Union requested state and federal agencies do after it conducted its own inquiry.
The Beijing Tourism Development Commission noted that the country's battle with pollution is another obstacle cities face in attracting inbound tourists.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

你要去里约看奥运会吗?你会在安卓或者iOS上装谷歌地图这个应用软件吗?我想你已经有了答案了。
1. Peaceful Era
rob
人们可能会认为,由于课程的灵活性,与全日制项目相比,在线MBA项目将更吸引女性。然而,2016年英国《金融时报》在线MBA排行榜的数据显示,女性占总学员数量的30%。在全日制项目中,女学员占到了35%。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

"My hair has turned white, half because of housing prices and half because of you reporters." JIANG WEIXIN, member of the CPPCC National Committee and minister of housing and urban-rural development, responding to media questions about government measures to curb housing prices
12月工业利润下滑突显出中国工业面临的产能过剩和价格下跌的困扰,这加大了中国政府放松货币政策并扩大基础设施支出,以缓和经济放缓影响的压力。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

周边环境:这栋房屋位于Kenwood社区,该社区分布着19至20世纪的都铎式、地中海式、维多利亚式和殖民地风格的建筑,在明尼阿波利斯市湖链区(Chain of Lakes)的锡达湖(Cedar Lake)与群岛湖(Lake of the Isles)之间。这里的道路蜿蜒曲折;人行道两边排列着枫树和白蜡树。据该房源的代理说,该社区许多较老的房屋都已翻修过,而近30年内建造的房屋都推倒重建了。
尽管该片被洛杉矶影评人协会评为最佳剪辑奖,但却没有受到纽约影评人的重视。它的势头会逐渐减弱吗?
In 2015, the number of migrant residents living in Shanghai dropped for the first time in the past 15 years, Shanghai Television reported Monday.
Girls Trip
节目17 小品《你摊上事儿了》,秦海璐 王茜华 孙涛 方清平

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

这些人当中,有些人会借助另一些问题表达他们的忧虑:贸易、犯罪、毒品战争、边境控制、对伊斯兰恐怖主义的恐惧。诚然,这些问题都很重要,也为许多人带来了真切的恐惧,但是它们已经变成一种方式,公众借助这些问题来讨论社会变革对于占多数的白人群体的影响。
The consumer price index rose by 1.8 per cent year-on-year in January, from 1.6 per cent in December 2015. However, CPI continues to trail Beijing’s target of “around 3 per cent“.
北京大学和北京外国语大学的2017届毕业生平均月薪分别为9042元和9020元,位居第二、三位。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

Consumer Electronics Show
中国保险企业2016年上半年利润出现大幅下滑。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 北京新机场人才公租房明年投用
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

否则,就应该交易考辛斯还有在过去的两个赛季里签下的其他的老将了。
There are lots of benefits to studying in a group. You have to be organized. You can't procrastinate. You have to really understand something to be able to explain it out loud to someone else.
这条新闻可能对经常坐飞机环球旅行的旅客们并不稀奇,新加坡的机场再一次做到了。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 京津冀建材向绿色功能转变提速
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

替代燃料:自从柴油车于上世纪50年代从欧洲进入美国以来,人们对柴油车的热情首次冷却殆尽,取而代之的是马力高得吓人的雪佛兰CamaroZL1(580匹马力),和707匹马力的道奇挑战者SRT地狱火等车型。另外,续航里程更长的燃料电池汽车也开始登上舞台,从电池动力汽车那里抢走了不少风头。
他们现在对阵克里夫兰和波士顿时的人员对位看起来顺眼多了。
给你我无尽的新的祝福,让它们成为我们永恒友谊的新的纪念。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

现在,库里和他的金州勇士队正行进在为创造又一个成就的正确道路上。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

《性别之战》

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

But John Davies, head of institutional investment in the Hong Kong team at CBRE, the property services business, says that lower prices should make the market more reliable. “The market is showing characteristics of a mature market, which institutional investors understand better,” he says.
这块白板经常被写满公式。但你是否曾好奇过这些公式都有什么含义?我们也许没有机会知道它们代表什么,但它们的确都是真实准确的公式。这一点相当给力。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

200911/88511.shtml
Despite it being not that different from the typical bottle opener, the BOx does have a nice design made with stainless steel and solid wood.
但舒尔茨没有停留在担心这一步。美国政府停摆期间,星巴克还在一些日子里为给他人买咖啡的顾客免单。舒尔茨希望此举能帮助人们“在期待民选官员为了国家利益团结起来的同时,彼此也能团结起来。”
节目26 相声剧《搭把手不孤独》,冯巩 郭冬临 闫学晶

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Experts waited until dark had fallen before detonating demolition charges which brought down 150000 square metres of concrete glass and steel in 10 seconds.
是的,这经常发生。你可以在家里,图书馆,打印店等除了你现在工作的公司办公室的任何地方打印申请材料。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

For many Western whites, opportunities for achieved identity — the top of the hill — seem unattainable. So their ascribed identity — their whiteness — feels more important than ever.
Christmas arrived on schedule for the U.S. auto industry as a spurt of sales put the wrapping on a surprisingly successful year. Analysts predicted that sales in December could hit a seasonally-adjusted rate of 17 million, which would be the first month at that rate in nearly six years. That would push 2013 sales up to a robust 15.7 million units.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

企业能否最终摆脱谨慎情绪?

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

6. Lighting
周二公布的数据显示,去年12月,中国规模以上工业企业利润同比下降8%,是2011年末以来的最大降幅。11月数据的同比下滑幅度为4.2%。
亲爱的朋友,你们即将毕业,呈现在你面前的世界拥有美好的前景和潜力;这个世界并不仅仅以办公室走廊或华尔街的形式出现,而是令人激动不已的真实世界,充满许多未解之谜,以及让人陶醉的体验。我们当中许多人都忽略了这个简单的真理。
The new data released yesterday represent the first snapshot of global trade for 2015. But the figures also come amid growing concerns that 2016 is already shaping up to be more fraught with dangers for the global economy than previously expected.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

The gold market may be obsessed about the dollar and prospect of a rise in US interest rates. But there’s another factor looming on the horizon: a fall in gold mine supply.
“…claimed he was late because he got lost, but our receptionist said she had seen him hanging out at the coffee shop.”

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

调查显示,大多数女性在求职时正在或者已经因性别偏见受到影响,因为雇主不愿意提供产假。为了避免雇主因需要付产假津贴和提高就业竞争力可能带来的歧视,据报道,一些女性求职者选择在大学毕业前结婚生子。
经济学人智库生活成本指数编辑乔恩?科派斯塔克表示,最显著的变化之一是澳大利亚生活成本的上升,它的两个城市悉尼和墨尔本分别名列第三和第五。夹在中间排名第四的是挪威的奥斯陆。
Not all the judges agreed with the book’s proposed solutions but nobody questioned the force of its argument.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

但多数白人常把民族和种族身份混为一谈。对很多白人来说,这种身份感觉像是支撑他们的世界最重要的支柱之一,而现在,它似乎受到了威胁。
截止发稿时为止,在中国社交媒体上仍然能够找到一些被泄露的照片和视频。
10.Shakira

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 新世纪光电完成5亿元再融资案
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

"The editors thought the articles were being sent out to genuine reviewers in the discipline," he said. "Following our investigation and communication with the real reviewers, they confirmed they did not conduct the peer review."
而传统主义者诸如乔治·克鲁尼(George Clooney),他因影片《逃离德黑兰》(Argo)获最佳影片奖以及在影片《辛瑞那》(Syriana )中获最佳男配角,他的奥斯卡奖杯放在家中的书房。达斯汀·霍夫曼(Dustin Hoffman)曾在1980年因影片《克莱默夫妇》(Kramer vs. Kramer) 、并在九年后因影片《雨人》(Rain Man)两次获最佳男主角奖,也将其奖杯放在书房中。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The Explore experience in Brazil is available on both iPhone and Android. Simply open Google Maps on your mobile phone and tap "explore food And drinks near you" at the bottom of the screen. Depending on where you are and time of day, Google Maps will share lists of food and drink locations around you, ranging from "best breakfasts" to "waterside dining", says Bryan Cheng, Product Manager, Google Maps.
201109/155435.shtmlIn August, Jose Javier - from the city of Torrevieja - created an account with AdWords, a Google pay-per-click service.
11月17日

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

n. 路线,(固定)线路,途径
节目31 京剧《迎来春色换人间》,于魁智 托马斯(孔子学院学员)

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 2013陶瓷市场年中盘点
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

中国企业家王兴(音)通过聊天软件“微信”(WeChat)与身在美国加州的姐姐和澳大利亚的叔叔保持联系。这款聊天软件让人得以一瞥中国网络公司怎样参与全球竞争。
年度最佳艺人:卢克·布莱恩
This raises the risk of heavy rains and flooding, scientists pointed out, because warmer temperatures would lead to more water vapour in the world’s atmosphere.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

Shares in Hyundai and AmorePacific slid on Friday, down 4.4 per cent and 12.5 per cent respectively in late afternoon trading in Seoul.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
From the themed collection: 前4月全国房地产开发投资2.54万亿
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

But then the story took a strange turn. Koudijs and Voth found that Dutch lenders reacted to the Seppenwolde collapse in strikingly different ways. Those who had made loans to Seppenwolde but hadn’t actually lost money became far more pessimistic and demanded much bigger haircuts from all new borrowers. But those who had dodged the bullet by not lending to Seppenwolde didn’t tighten their requirements at all. In fact, those lenders slightly reduced haircuts to their borrowers – a sign they were at least as sanguine as before.
其实,中国经济增速放缓至8%左右,对中国乃至世界都是一件好事。更具环境可持续性、更加公平的局面,将缓解社会忧虑,而更高的消费将缓解全球贸易紧张。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Sandy has caused large-scale damage, with more possibly to come.
广义货币M2增长11.3%,低于13%左右的预期目标;

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

10. Computer systems analyst
Wonder Woman

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Did you write The Lego Batman Movie off as kids-only? Biggest mistake ever. This movie is a witty feat of hilarity, full of dry humor and moments of comedy gold. Basically, if you like Will Arnett in Arrested Development, you will like this.
“An employee left a sticky note saying that he was quitting.”

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

25 July

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
From the themed collection: 7日内房股全线大涨 恒大涨幅超21%
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

syndrome
1.take hard classes
据预测,在大宗商品价格上涨和需求温和上升的推动下,2017年以美元计的新兴市场国家出口额将出现自2014年以来的首次增长。
但许多人预测将会出现经济崩盘,他们认为,旷日持久的欧元区危机加上房地产泡沫,将使相当大一部分中国工业失去盈利能力。这将暴露出各种隐藏的金融脆弱性,推动形成一场螺旋式下降。其他人认为,北京方面有充足的资源可以避免一场危机,不过他们指出,由于中国的增长模式依赖于基建和土地出售,且汇率和利率受到僵硬控制,它也许并没有所有必要工具。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Will the UK economy be the slowest-growing in the G7

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

三大能源机构近期表示,今年石油输出国组织(Organization of the Petroleum Exporting Countries, 简称:欧佩克)以外国家的原油产量将增加,其中大部分来自美国的页岩油。除此之外,由于伊朗、伊拉克和利比亚可能会增产,中东地区的原油产量也许会增加数百万桶。所有这些势必会令油价承压。
巴蒂表示,中国的大学现如今已经花费百万元巨资聘请国际知名学者,同时还配备了各项最先进的设备。
Margot Wallstrom

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 深圳:坚持不懈保障和改善民生
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

加一些颜色。丰富的颜色可以让你充满活力。如果可以的话,可以选择一些色彩鲜艳的桌子和椅子。
伯利兹城最富盛名的旅游胜地莫过于巨大的水下天坑--蓝色巨洞以及玛雅遗址。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Iron Man was Downey’s only movie of 2013, while Johnson had one huge film, Fast & Furious 6; one big film, G.I. Joe: Retaliation; and two smaller films. Together they added up to $1.3 billion at the global box office.
那么,于汽车业而言,2015年又意味着什么?以下是一些有根据的猜测。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

China has all long and continues to support a united, prosperous and stable European Union, support a strong Euro, and support European integration process. We believe that is good for globalization, for a multipolar world and for diversity of civilizations. We feel optimistic about the future of the EU and the future of China-EU relations.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

People with Type A personalities are often high-achieving "workaholics". They push themselves with deadlines, and hate both delays and ambivalence. People with Type A personalities experience more job-related stress and less job satisfaction.
Learn to control your emotions, control your thoughts, get over fear of rejection and learn to open up.
安吉利拉瓦尔(Anjli Raval)

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

愿新年的快乐一年四季常在。
delicate
“图特摩斯三世是埃及新王朝最重要的法老之一。他使埃及在迦南完成了从一个地域性王国向洲际大帝国的质变。”“圣殿山筛选项目”的联合发起人和总负责人Gabriel Barkay如是说。
智联招聘高级职业顾问王一新表示:“虽然国家政策、各大高校和投资环境给大学生创业提供了良好的土壤,但鉴于大学生经验欠缺、资源积累不足、人脉不足等原因,目前大学生创业成功的概率并不高。”

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Will Emmanuel Macron secure a commitment from German chancellor Angela Merkel on a eurozone budget
当小李子上台领取奖杯时,制片人哈维·韦恩斯坦兴奋地拍拍他的背,全场观众起立为他喝彩。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

该银行在其报告中称:中国是否减持库存将成为2017年棉花和糖市场的主要价格推动因素,玉米、大豆或植物油可能也是如此。
……被要求向面试官简单介绍自己,结果她没有什么可说的。
鉴于计算机编程被冠以“美国经济中尚未开垦的处女地”称号,纽约编程及设计学院正在努力让“谈论”代码变得更简单。到2020年,美国市场上将会有150万个计算机科学相关岗位,而计算机科学专业毕业生则仅有40万人。此外,计算机科学相关岗位在全美的平均增长率是其他职位的两倍。但是如果你并没有计算机科学专业学位,也没有计划重返校园又该如何呢?纽约编程及设计学院通过提供夜校课程和密集型研讨会的方式正在令学习网络设计和开发变得简单——从该项目毕业后,创建一家全新的网站,或是着手寻找技术相关的职位,并不是什么稀罕的事情。正如创始人杰瑞米?司乃帕(Jeremy Snepar)所言,在当下的数字化经济中,你不能不懂得怎样编程。他将编程看做是一种技术能力,一种能够也应该以更为简单的方式学习的能力,而纽约编程及设计学院正是为那些曾经感慨过“如果我懂怎样编程就好了”的人填补了一个重要的空白。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

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Attractions: Paradise within reach.
最新的官方资料显示十二月中旬的数据大幅增长,有1200人已经离开或者正谋求去战场加入圣战份子。

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